No chemo? Triangle doctors excited by new findings for breast cancer patients

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Most girls with the most Frequent kind of early-stage Breast cancer may safely bypass chemotherapy without damaging their chances of beating the illness, physicians are reporting from a landmark study that used genetic testing to evaluate every individual's risk.

He says breast cancer patients fall into three categories: Low-risk, which does not require chemo, high-risk - which demands the treatment, and an intermediate category they call "the grey area", where he says this new research now clarifies.

Around half of women taking aromatase inhibitors, a common drug for postmenopausal women with hormone receptor positive breast cancer, experience joint pain.

The study focused on those women with a mid-range recurrence score of 11-25, as uncertainty still remains as to whether chemotherapy is beneficial for this group.

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"For women over 50, we can feel quite confident that using the data in this trial to prevent the use of chemotherapy for women with those scores".

Approximately 17 percent of girls needed high-risk scores and have been counseled to have chemo. Many women think "if I don't get chemotherapy I'm going to die, and if I get chemo I'm going to be cured", but the results show there's a sliding scale of benefit and sometimes none, he said.

After nine Decades, 94 percent of both teams were still living, and About 84 percent were living with no signs of cancer, therefore adding chemo made no real difference.

Cancer care has been evolving away from chemotherapy - older drugs with harsh side effects - in favor of gene-targeting therapies, hormone blockers and immune system treatments.

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An analysis of a 2015 study of 249 patients found Omega-3 helped relieve symptoms among obese women taking the drug, who are more likely to experience joint pain.

Over the years, the Cancer Institute has used its $59.8 million in proceeds for studies trying to improve early detection and to determine which cancers are most unsafe and need heaviest treatment and which are less so.

The new results demonstrate that chemotherapy is not beneficial for most women in the intermediate-risk group. "The trial was created to address this question and provides a very definitive answer", said Dr. Sparano. These come from small, early stage studies through to large randomised clinical trials.

The study was supported in part by the Breast Cancer Research Foundation, Komen Foundation, and the Breast Cancer Research Stamp. "Any woman with early-stage breast cancer age 75 or younger should have the 21-gene expression test and discuss the results with her doctor to guide her decision to the right therapy".

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