The first of three one-day internationals against India at Trent Bridge sees Root restored to the England middle order after being dropped for the first time in four years for Sunday's Twenty20 decider.
The chase was a stroll in the park as the runs were knocked off in only 40.1 overs courtesy Rohit's (137 not out).
Rohit Sharma, to the delight of the many India fans in a sun-drenched capacity crowd of over 17,000, then made an unbeaten century as the tourists won by eight wickets with a mammoth 59 balls to spare.
He bowled an astounding 38 dot balls and not once was he hit for a boundary. This was Kuldeep's first five-for in ODIs after he had achieved the same feat in T20Is during the Manchester encounter.
However, England still played well and if they'd got a few more runs on the board we would be sat here with a slightly different story going into this three-match one-day series.More news: Meghan Markle high-fives children at Croke Park during visit
After winning the T20I series against England, India is all set to start the ODI series against the Englishmen.
With the ball, spinners Adil Rashid and Moeen Ali will be a major threat to the visitors.
England looked shaky at 105-4, after captain Eoin Morgan was caught by Suresh Raina off Yuzvendra Chahal, but Buttler (53) and Ben Stokes (50) restored some calm with half-centuries before Kuldeep struck again.
With cricket's blue riband tournament scheduled to be held in United Kingdom next year, the ODI series will give Virat Kohli an ideal opportunity to get a drift about the conditions that his men are expected to encounter at exactly same time next year.
Such was Kuldeep's brilliance that it prompted Kohli to hint that the chinaman bowler might feature in India's Test XI against England later on. His decision was not proving to be the best as England openers Jonny Bairstow and Jason Roy were scoring at 8 runs per over.More news: Kylie Jenner trolled after Forbes names her 'self-made' billionaire
They added 73 for the opening stand before a wrong execution of reverse sweep brought about Roy's downfall.
But the introduction of Kuldeep for the 11th over changed the course of the match and it took him just two balls to strike.
Eoin Morgan's men brushed aside Australia with relative ease in their five one-day global matches and solitary T20 contest. Some played with the turn and some tried against the turn - both with dismal outcomes.
However, England has been ruthless in the format of late, having posted mammoth total of 400 plus runs, twice this year. Four balls later, Bairstow was trapped lbw via DRS, failing to read the googly.
England had collapsed to 82 for three, losing three wickets for nine runs in the space of 16 balls. "It's hard because of the limited opportunities I've had to play T20 cricket, but the thing that has always been at the forefront of my mind is that playing for England comes first".More news: The Peter Strzok fiasco wrecks the GOP’s bogus conspiracy theory
Stokes and Buttler staunched the flow of wickets without breaking the shackles.