The major issue is at left-back, where Sead Kolasinac is definitely out and Nacho Monreal is considered doubtful, which may mean Ainsley Maitland-Niles starting.
Manchester City have no injury concerns but there are questions over a few squad members match fitness following their late returns to pre-season training.
There could be debuts for Torreira, Sokratis and Leno, as the German is indeed considered as Arsenal's new No.1, ahead of veteran Petr Cech.
The match can be viewed on Sky Sports Premier League in the UK.More news: Nasa spacecraft heads to sun for closest look yet
If it's a 4-3-3 Ozil will play from the right, although won't relish the prospect of tracking back with Benjamin Mendy.
Aaron Ramsey, playing at the top of the midfield trio, had some bright moments in the early stages but struggled to get on the ball after City's dominance had become established. So, the fans looking to catch Arsenal vs Manchester City football match online will have to access Hotstar app or website for live online streaming.
Arsenal will step out under new a manager for the first time since 1996.
There was much debate prior to today on who will be the centre back pairing with Pep Guardiola confirming a more youthful option of John Stones and Aymeric Laporte over captain Vincent Kompany and Nicolas Otamendi.More news: Former Brazilian superstar footballer Ronaldo in intensive care
Former Arsenal defender Keown believes the Gunners have an outside shot of a top-four finish in the Premier League next term.
Unai Emery is clearly not afraid to experiment.
City made just one signing over the summer as Riyad Mahrez arrived from Leicester, but despite their lack of acquisitions, it would be hard to bet against City being even better in 2018/19.
Whereas last season Guardiola used advanced wingers stretching the play and going in behind, often with more conservative full-backs, here his approach was different.More news: How major USA stock indexes fared Friday
A summer of transition had taken centre stage at Emirates Stadium this summer with Arsene Wenger leaving after 22 years at the helm. His clinical nayure and proper positioning will make him a threat for City, and he indeed is the one player to watch out for when the two sides meet.