First, though, both get what shape up as mismatches in the fourth round: Federer plays 55th-ranked John Millman, and Djokovic faces 68th-ranked Sousa.
Federer would knock Kyrgios out 6-4, 6-1, 7-5 at the US Open on Saturday, which isn't shocking in itself.
Gracious himself in defeat, Kyrgios lamented not converting any of four break-point chances in the seventh game of the opening set, in which he had Federer down love-40. He has now become the first ever player from Portugal to reach the fourth round of a grand slam in singles.
"It was nearly unreal", said Kyrgios, who is no stranger to trick shots of his own. The Australian, who plays Roger Federer in the fourth round, had to rescue Ron after he took the wrong bus trying to find his son's flat for Wimbledon.More news: Barack Obama Slams Donald Trump In Speech - 'He's Capitalizing On Resentment'
"For a shot like this to happen in a practice, you will be running into a fence and you will hit it into the net", he said.
Kyrgios was already scrapping to stay in the match when Federer produced a moment of magic. I don't want to go back to when I was a little kid.
"It was the best match of the week so far without a doubt, and one of the best performances of the hardcourt season after Wimbledon", said Djokovic, who warmed up for Flushing Meadows by beating Federer in the Cincinnati Masters final.
If you thought Maria Sharapova would be challenged by the next generation star Jelena Ostapenko, the Russian answered by continuing her night match win-streak, clocking in her 23rd U.S. Open evening victory, 6-3, 6-2.
From there, Federer served out the match easily to set up a fourth-round clash with another Australian, John Millman. Also that he's been using my serve sometimes to great effect, which I'm very happy to see.More news: Cher coming to St. Louis in 2019
Early on, tensions ran high for Kyrgios, who was overheard berating his camp, which appeared to be encouraging him to get in his first serve.
Sabalenka will play Japan's Naomi Osaka, who crushed Aliaksandra Sasnovich 6-0, 6-0.
But he said no matter what he tried, Federer had the answers.
Djokovic saved all five break points he faced to book a meeting with Joao Sousa of Portugal, a 7-6 (7/5) 4-6 7-6 (7/4) 7-6 (7/5) victor over France's Lucas Pouille.
American hopeful Madison Keys rallied after dropping the first set to beat Aleksandra Krunic 4-6 6-1 6-2 on Saturday.More news: Attacks in Afghanistan Kill 6 Police