Mr Trump and his fellow Republicans said the new Federal Bureau of Investigation report had cleared their nominee.
As protesters in a Capitol Hill hallway shouted, "Shame!" Around 100 of them were detained by the police.
Trump's reference to Soros, who has supported pro-democracy movements around the world and the US Democratic Party for years, appeared to aim at inciting more support and anger from the president's conservative Christian base. Kavanaugh has denied the allegation.
"We will see what happens tomorrow", said Murkowski. It would be the closest roll call to confirm a justice since 1881, when Stanley Matthews was approved by 24-23, according to Senate records.
In a signed declaration, he shared an account of two interactions he had with Ford in which she spoke about Kavanaugh's alleged sexual assault years before he was nominated to the Supreme Court. Both he and Collins attempted to express a belief that Dr. Blasey Ford was assaulted, but not by Kavanaugh.More news: Noble deeds go unnoticed by Nobel committee
"Me", Rice responded. Psaki said any Collins opponent would be "well-funded". "We must always remember that it is when passions are most inflamed that fairness is most in jeopardy".
According to a Capitol Hill police officer, authorities are investigating a female protester allegedly assaulting a man outside Collins' office, and two people have been detained and are now being questioned.
Lisa Murkowski (R-AK) voted "No" on cloture this Friday only to follow it up with an announcement that she will vote "No" on the final vote. "And my heart goes out to anyone who has experienced any type of sexual assault in their life".
Republicans control the Senate by a meager 51-49 margin. Manchin of West Virginia. A few Democrats sat stone-faced nearby.
Senator Collins backed the embattled pick.
Under the pairing arrangement, the senator in the duo who is present and voting - in this case Murkowski - announces that she or he has "a pair" with the senator not in attendance.More news: Rangers 3-1 Hearts: Title race 'blown wide open' - Steven Gerrard
Politically, with a chance of increasing his majority in the midterm elections, McConnell said the GOP is already seeing improvement in polling on Senate races due to the Democratic opposition to Kavanaugh combined with the protests. She said, however, that she sets a high bar for nominees to win confirmation and talked about the importance of selecting judges who will act at all times in a manner that promotes "public confidence" in the judiciary. "And that is hard". Steve Daines, R-Montana, can make it to the floor in time for the vote, as he is attending his daughter's wedding Saturday.
The Maine senator is under enormous pressure to vote for Kavanaugh, and she has indicated that she is leaning in that direction. In 2017, Collins was a swing vote that helped save the Affordable Care Act of 2010, a.k.a. Obamacare, from being overturned-and unlike most Republicans, Collins is pro-choice on the abortion issue.
Vice President Mike Pence planned to be available Saturday in case his tie-breaking vote was needed, which now seems unlikely.
The Senate voted 51-49 to limit debate, effectively defeating Democratic efforts to scuttle the nomination with endless delays. The House voted to impeach him in 1804 on counts that he had let his political bias sway his rulings, but he was acquitted of all counts by the Senate.
On the other side, Senate Democratic leader Chuck Schumer of NY called the fight "a sorry epilogue to the brazen theft of Justice Scalia's seat".More news: Trio win Nobel Chemistry Prize for 'a revolution in evolution'