World's first baby born via womb transplant from dead donor

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Brazilian doctors said the first baby has been born to a woman with a uterus that was transplanted from a deceased donor, reports say.

Infertility affects one in seven people in Britain, and while some problems can be solved through IVF, most women with womb issues have no alternative but adoption or surrogacy.

The first baby born from a woman who recieved a uterus transplant from a dead donor is healthy a year on.

In a landmark move, a baby in Brazil has been born to a woman with a transplanted uterus from a deceased donor.

Singer stressed that pregnancies involving transplanted uteruses from deceased donors have failed in the past, but the Brazilian case is "an exciting step in the right direction". Flyckt and her colleagues in Cleveland have also performed two transplants from deceased donors.

Five months after the transplant, Ejzenberg's team wrote, the uterus showed no signs of rejection, ultrasound scans were normal, and the recipient was having regular menstruation.

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The whole field of uterus transplantation is in its early days. According to research cited by the authors, 10 to 15 per cent of couples who could theoretically have and want children are infertile in some way, with one in 500 women in this population being infertile due to the lack of a uterus.

She added, however, that the outcomes and effects of womb donations from live and deceased donors have yet to be compared, and said the technique could still be refined and optimised.

In the USA, around 10 percent of women aged between 15 to 44 struggle with fertility, according to the Centers for Disease Control and Prevention.

Doctors said in the study that the woman felt "fulfilled" by the chance to carry and deliver her own daughter in spite of her condition. She gave birth to a baby girl on December 15, 2017, by caesarean section.

Uterine transplants from living donors have occurred before.

"The use of deceased donors could greatly broaden access to this treatment, and our results provide proof-of-concept for a new option for women with uterine infertility."the lancet quoted the lead researcher Dr Dani Ejzenberg, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo". "However, the need for a live donor is a major limitation as donors are rare, typically being willing and eligible family members or close friends". Andraus explained it was important the donor had to be around 45 years old since it becomes harder to retrieve the uterus without complications in older women, and the donor must have given birth at least once in the past to prove her uterus was viable, he said in an interview with The Lancet, a medical journal.

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There have been a total of 39 live donor transplants, resulting in 11 live births in the past five years. Seven months after the surgery, an embryo was implanted and her pregnancy was confirmed.

While researchers in countries including Sweden and the U.S. have previously succeeded in transplanting wombs from living donors into women who have gone on to give birth, experts said the latest development was a significant advance.

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The baby, weighing 2,550 grams at birth, remains healthy and develops normally 7 months after birth.

Some who were born without a uterus, other had unexplained malformations, of sustained damaged during childbirth or infection.

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