The government, meanwhile, appealed to the jury not to let Guzman escape - an allusion to his two spectacular jail breaks in Mexico, the last one in 2015 through a tunnel from a shower area in his cell.
One of the trial's most memorable pieces of evidence came from El Chapo's mistress Lucero Guadalupe Sanchez Lopez, who testified she was in bed in a safe house with an on-the-run Guzman in 2014 when Mexican marines started breaking down his door.
The defense called just one witness, an Federal Bureau of Investigation agent put on the stand in an attempt to undermine the credibility of one of Guzman's cocaine suppliers who had testified against him.
The identities of jurors were kept for their safety and to try and stop the Mexican drug lord, real name Joaquin Guzman, from getting his cronies to sway the verdict with bribes or threats.
Read the full report at the New York Post. When the jurors were discharged, he leaned back in his chair to catch the eye of his wife, who gave him a subtle thumbs-up.
In this courtroom drawing from February 7, Joaquin Guzman listens to Judge Brian Cogan addressing the jury. Cogan says it made him "very proud to be an American".More news: Iran Marks 40th Anniversary of Revolution
He could face life behind bars in a maximum security US prison.
Federal prosecutors say a jury has reached a verdict in the USA trial of Mexican drug kingpin Joaquin "El Chapo" Guzman. His sentencing is set to be announced on June 25th.
Even when Guzman was recaptured in 2016 before his extradition to the United States, he was plotting another escape, prosecutor Andrea Goldbarg said in closing arguments.
The 11-week trial featured testimonies from more than 50 witnesses and offered one of the most detailed insights into the Sinaloa Cartel - named after the state in Mexico where El Chapo was born - ever.
Guzman, 61, was extradited to the U.S.in 2017 after Mexican authorities captured him a year prior during raids in Los Mochis, Sinaloa.
After three months of testimony, jurors have reached a guilty verdict on all 10 counts.More news: California governor decries 'political theater' as Trump heads to border
U.S. District Judge Brian Cogan lauded the jury's meticulous attention to detail and the "remarkable" approach it took toward deliberations.
The trial testimony lasted almost three months and the jurors have been tasked with deciding on 10 separate counts.
Federal prosecutors say Guzman's Sinaloa cartel amassed billions of dollars importing tons of cocaine, heroin and marijuana into the U.S. Fourteen of those witnesses - mostly admitted drug traffickers and cartel associates - were cooperating with prosecutors in hopes of reducing their own prison sentences.
Jurors at the US trial of Mexican drug kingpin Joaquin "El Chapo" Guzman are in their sixth day of deliberations.
They were escorted to and from the fortress-like Brooklyn courthouse by US Marshals during each day of the 35 day trial, which saw 56 prosecution witnesses called to testify against El Chapo.
The most detailed evidence against Guzman came from more than a dozen former associates who struck deals to cooperate with USA prosecutors.More news: China posts video claiming Uighur poet reported dead in detention is alive