On Wednesday, a little after 9 p.m., Cali - who went by Frank rather than Francesco- was shot multiple times in the torso outside of his Staten Island home, New York Police Department confirms to PEOPLE.
He was pronounced dead at a hospital soon after.
An alleged mafia boss has been reportedly been shot and killed outside his home in NY.
Reputed Gambino Crime Boss Frank Cali Shot Dead In Front Of Staten Island Home
Authorities are investigating Cali's death, and some media reports note a blue pickup was seen leaving the scene shortly after the shooting.
Police said the motive was not known.
The Gambino Family was once among the most powerful criminal organizations in the US, but federal prosecutions in the 1980s and 1990s sent its top leaders to prison and diminished its reach. His head was by his SUV, and the truck was open'.More news: Drug Charge Results in Halted Sales of ‘Yakuza’ Spin-Off Game ‘Judgment’
"Papa! Papa!" one man cried before laying down on the grass, sobbing, the witness recounted. Papa!' as a woman shouted into her phone: 'Why doesn't the ambulance come?
The Gambino crime boss was assassinated outside Sparks Steakhouse in Manhattan in 1985.
"Cali is seen as a man of influence and power by organised crime members in Italy", US assistant attorney Joey Lipton told the court, the New York Daily News reported at the time.More news: After Closed Meeting, Nadler Makes New Claims About Whitaker's DOJ Conduct
In 2008, Cali was arrested and charged with federal racketeering as part of Operation Old Bridge - a code name for the February 7 arrests in Italy and the USA that targeted the Gambino crime family.
Cali himself was jailed for 16 months for his connection to an extortion scheme surrounding an attempt to build a NASCAR track on Staten Island.
The Gambinos" rise to become one of the most powerful mafia families in America started in 1957, when the family's namesake, Carlos Gambino - an Italian immigrant - orchestrated the murder of Albert Anastasia, who had organized a collection of Italian gangs into what now would be considered a "crime family'.More news: US prosecutors probing Facebook's data deals, New York Times says